|
Oroya fever or Carrion's Disease is an infectious disease produced by ''Bartonella bacilliformis'' infection. It is named for Daniel Alcides Carrión. ==History== Carrion's disease has been known since Pre-Inca times. Numerous artistic representations in clay (called "huacos") of the chronic phase have been found in endemic areas. The Spanish chronist, Garcilaso De La Vega described a disease with warts in Spanish troops during the conquest of Inca Empire, in Coaque-Ecuador. For a long time it was thought that the disease was endemic only in Peru and that it had only one phase, the "Peruvian wart" or "verruga peruana"〔Maguiña, C., 1998. Bartonellosis o Enfermedad de Carrión. A.F.A. Editores Importadores S.A., Lima.〕 In 1875 an outbreak, characterized by fever and anemia occurred in the region of construction of the railroad line between Lima and Oroya. This is the source of the name "oroya fever" sometimes used to describe acute bartonellosis. In August 1885, Daniel Alcides Carrión, a Peruvian medical student, attempted to inoculate himself with material taken from a verruga lesion of a chronic patient (Carmen Paredes), with the help of a local physician (Evaristo Chavez). After 3 weeks he developed classic symptoms of the acute phase of the disease, thus establishing a common etiology (cause) for these two diseases.〔Schultz MG. Daniel Alcides Carrión (photo quiz). Emerg Infect Dis. 2010 Jun. Available from http://www.cdc.gov/EID/content/16/6/1025.htm Accessed 26 May 2010.〕 He died from bartonellosis on October 5, 1885 and was recognized as a martyr of Peruvian medicine and the term Carrión's Disease was used until our times (Peruvian Medicine Day is October 5 in honor to him). Alberto Barton, a Peruvian microbiologist, identified ''Bartonella bacilliformis'' within erythrocytes in 1905, an announced the discovery of the etiologic agent (Barton bacillus) in 1909, which was called ''Bartonella bacilliformis''. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Carrion's disease」の詳細全文を読む スポンサード リンク
|